arXiv:2610.37431v1 Announce Type: new Abstract: Convolutional neural networks (CNN) are widely used for medical image segmentation. However, they lack an inherent measure of confidence. Existing methods for estimating prediction uncertainty often require a custom network architecture and/or dedicated training setups and need to be trained from scratch. In addition, the deduction of a single confidence score per input from the uncertainty maps is not always straightforward. In this study, we explore voxel-based uncertainty estimation methods that can be added to existing segmentation pipelines without training from scratch. We also propose a novel method to estimate a single confidence score from the uncertainty maps. Our evaluations on different ROIs and modalities suggest that our confidence score can predict segmentation performance in unseen data.